Al despertar solo en un extraño hotel y habiendo perdido la memoria, John Murdoch se ve envuelto en una peligrosa búsqueda de su identidad en una ciudad donde la noche parece nunca terminar, mientras es perseguido por las autoridades como el autor de una serie de sádicos y brutales asesinatos.
Sinopsis en inglés:
John Murdoch awakens alone in a strange hotel to find that he has lost his memory and is wanted for a series of brutal and bizarre murders. While trying to piece together his past, he stumbles upon a fiendish underworld controlled by a group of beings known as The Strangers who possess the ability to put people to sleep and alter the city and its inhabitants. Now Murdoch must find a way to stop them before they take control of his mind and destroy him.